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Contraindicated (1)pentobarbital will lower the level or impact of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with potent CYP3A4 inducers can lead to decreased serum concentrations and lack of antimalarial efficacypentobarbital will lower the extent or impact of etravirine by impacting h